July 26, 2020
Satisfaction of Spatial Restraints of Comparative Protein
Comparative protein modelling by satisfaction of spatial restraints. We describe a comparative protein modelling technique designed to search out essentially the most possible construction for a sequence given its alignment with associated buildings. The three-dimensional (3D) mannequin is obtained by optimally satisfying spatial restraints derived from the alignment and expressed as chance density capabilities (pdfs) for the options restrained. For instance, the chances for main-chain conformations […]